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Cortical depth changes in enriched and isolated mice
Author(s) -
Cummins R. A.,
Livesey P. J.,
Bell J. A.
Publication year - 1982
Publication title -
developmental psychobiology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.055
H-Index - 93
eISSN - 1098-2302
pISSN - 0012-1630
DOI - 10.1002/dev.420150302
Subject(s) - cortex (anatomy) , cortical neurons , stimulation , environmental enrichment , cerebral cortex , biology , occipital region , medicine , anatomy , neuroscience
The occipital cortical depth was determined in laboratory mice at both 14 and 20 days of age and after various periods of postweaning exposure to enrichment or isolation. The depth was found to be maximal at 20 days of age. It declined thereafter, irrespective of environment, but the isolate cortical depth decreased faster than the enriched. The postweaning depth of the occipital cortex appears to be determined by an inevitable age‐related decrease whose rate of decline may be attenuated by sensory stimulation. The postweaning cortical depth may reflect the extent of cortical neuronal development and associated metabolic activity.