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Long‐term effects of preweaning taurine injections in rats: Interactions with strain and gender
Author(s) -
Valliant Paul M.,
Persinger Michael A.,
Satinder K. Paul
Publication year - 1979
Publication title -
developmental psychobiology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.055
H-Index - 93
eISSN - 1098-2302
pISSN - 0012-1630
DOI - 10.1002/dev.420120511
Subject(s) - taurine , saline , defecation , open field , endocrinology , strain (injury) , medicine , zoology , biology , psychology , chemistry , biochemistry , amino acid
Abstract A comparison was made of MR, MNR, and RCA strains that had been injected with either 62.5 mg/kg of taurine or comparable volumes of physiological saline between postnatal Days 8 and 20 and later tested at 100 days of age in an open field and 1‐way shock avoidance situations. Taurine‐injected rats displayed significant elevation in defecation score in the open field. In addition a significant Treatment × Strain interaction was due to the larger defecation numbers displayed by the taurine‐injected MR rats relative to the saline‐injected MR rats.