Behavioral effects of neonatal thyroid hormones and differential postweaning rearing in rats | Zendy

Sjödén PerOlow | Zendy; Lindqvist Mats | Zendy

AI Assistant Blog Pricing

Home ZAIA Blog

Premium

Behavioral effects of neonatal thyroid hormones and differential postweaning rearing in rats

Author(s) -

Sjödén PerOlow,

Lindqvist Mats

Publication year - 1978

Publication title -

developmental psychobiology

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 1.055

H-Index - 93

eISSN - 1098-2302

pISSN - 0012-1630

DOI - 10.1002/dev.420110410

Subject(s) - open field , endocrinology , medicine , microgram , hormone , differential effects , psychology , thyroid hormones , differential reinforcement , developmental psychology , reinforcement , biology , in vitro , biochemistry , social psychology

Male and female rats (T rats) given an injection of 75 μg tri‐iodothyronine (T 3 ) and 25 μg thyroxine (T 4 ) on Day 3 after birth were raised under enriched (E) and impoverished (I) postweaning conditions. Observations of their open‐field behavior on Days 63 and 112 revealed a higher rate of activity in T groups as compared to controls (C) as well as faster running times and more entries/min in Hebb‐Williams maze testing on Days 74–86, indicating behavioral hyperactivity in T rats. Active‐avoidance testing at age 91 days revealed a higher number of intertrial crossings and significantly faster unconditioned response and conditioned response latencies in T as compared to C groups. Enriched postweaning rearing altered the behavioral effects in T rats comparatively little, least in the open‐field and more so for escape‐ and avoidance‐latencies and for the number of errors in the Hebb‐Williams maze.

This content is not available in your region!

Continue researching here.

Having issues? You can contact us here

Accelerating Research