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Aversive prenatal stimulation: Effects on behavioral, biochemical, and somatic ontogeny in the rat
Author(s) -
Sobrian Sonya K.
Publication year - 1977
Publication title -
developmental psychobiology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.055
H-Index - 93
eISSN - 1098-2302
pISSN - 0012-1630
DOI - 10.1002/dev.420100107
Subject(s) - ontogeny , offspring , stimulation , endocrinology , reflex , medicine , psychology , serotonin , pregnancy , biology , receptor , genetics
Abstract Electric foot shock administered to pregnant rats altered the ontogeny of spontaneous motor activity in their pups. Prenatally stimulated (PMS) offspring were more active than controls on Days 1–10 but less active during the 3rd postpartum week. The age of peak activity, a major developmental landmark, occurred in PMS pups around 10 days of age; in controls maximum activity was not seen until the 3rd week. This effect was independent of the gender of the offspring and the timing of the gestational stimulation. Its appearance in both cross‐fostered and fostered pups indicated the prenatal origin of the effect. The maturation of spontaneous alternation behavior and several reflexes and the appearance of physical features were not affected by prenatal stimulation. Moreover, both PMS and control groups exhibited an age‐related increase in brain concentrations of norepinephrine, serotonin, and 5‐hydroxyindoleacetic acid. These findings indicate that spontaneous motor activity is uniquely sensitive to PMS, and as far as can be determined here, PMS produces no generalized alternation in behavioral and physical ontogeny.