Visual sensitivity to orientation of rectangles in mice with retinal degeneration | Zendy

Schnitzer Samuel B. | Zendy; Beane Millard E. N. | Zendy

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Visual sensitivity to orientation of rectangles in mice with retinal degeneration

Author(s) -

Schnitzer Samuel B.,

Beane Millard E. N.

Publication year - 1976

Publication title -

developmental psychobiology

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 1.055

H-Index - 93

eISSN - 1098-2302

pISSN - 0012-1630

DOI - 10.1002/dev.420090209

Subject(s) - retinal degeneration , orientation (vector space) , strain (injury) , retinal , psychology , degeneration (medical) , inbred strain , task (project management) , audiology , ophthalmology , biology , anatomy , medicine , mathematics , genetics , geometry , management , gene , economics

C 3 H/HeJ male mice, an inbred strain showing retinal degeneration ( rd ), and normal‐eyed DBA/1J male mice were studied in a task requiring discrimination of horizontally and vertically oriented rectangles. The apparatus was a modified Yerkes discrimination apparatus. The mice were given 30 days of discrimination training, 10 trials/day, after which 10 more trials were given on the 31st day with positive and negative cues reversed. Both strains showed a highly significant decrease in errors during acquisition, the rd strain making significantly fewer errors than the DBA/1J animals. Reversal of the cues brought about a sharp increase in percentage of errors.

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