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Ovarian influences on the development of sexual behavior in neonatally androgenized rats
Author(s) -
Hendricks Shelton E.,
Duffy John A.
Publication year - 1974
Publication title -
developmental psychobiology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.055
H-Index - 93
eISSN - 1098-2302
pISSN - 0012-1630
DOI - 10.1002/dev.420070405
Subject(s) - testosterone propionate , ovariectomized rat , medicine , endocrinology , testosterone (patch) , sexual behavior , physiology , psychology , estrogen , developmental psychology , androgen , hormone
Abstract Female sexual behavior was studied in male and female rats. Males were castrated on the day of birth (Day 1); some received ovarian implants at that time; others were injected on Day 3 with oil, 5 μg testosterone propionate (TP), or 50 μg TP. Females were ovariectomized at birth, 20, or 60 days of age; on Day 3 all were injected with oil, 5 μg, TP, or 50 μg TP. Prepuberal ovarian tenancy in females tended to counteract the effects on sexual receptivity of TP administered during neonatal life. In males ovarian implants facilitated female sexual behavior at adulthood in oil‐injected animals, but did not significantly influence the effect on neonatally injected TP.