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Inception of a 24‐hr memory capacity in two mouse strains
Author(s) -
Nagy Z. Michael,
Misanin James R.,
Wetzel Barbara
Publication year - 1973
Publication title -
developmental psychobiology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.055
H-Index - 93
eISSN - 1098-2302
pISSN - 0012-1630
DOI - 10.1002/dev.420060608
Subject(s) - litter , memory retention , retention time , zoology , psychology , medicine , physiology , audiology , biology , chemistry , neuroscience , ecology , chromatography
Abstract Separate groups of C3H and Swiss‐Webster (S‐W) mice received 25 escape training trials in a straight alley at 8 or 10 days of age. Each of these groups was then divided into 3 retention groups, receiving an additional 25 training trials, 1, 6, or 24 hr following original training. Comparisons of the retest scores with original training scores, as well as with litter‐mate controls without prior training, indicated that both strains trained at 8 days of age failed to demonstrate retention of learning when retested 24 hr after training, although they showed reliable 1‐hr retention and some evidence of 6‐hr retention. However, mice trained at 10 days of age performed better on the retention tests at all retest intervals than they had on original training, as well as better than maturation controls without prior training. These results indicate that a 24‐hr retention capacity for escape training develops between 8‐10 days of age in both mouse strains.