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The interaction of genotype and exogenous neonatal androgen and estrogen: Sex behavior in female mice
Author(s) -
Vale Jack R.,
Ray Donald,
Vale Carol A.
Publication year - 1973
Publication title -
developmental psychobiology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.055
H-Index - 93
eISSN - 1098-2302
pISSN - 0012-1630
DOI - 10.1002/dev.420060405
Subject(s) - genotype , androgen , estrogen , endocrinology , hormone , medicine , testosterone (patch) , biology , genetics , gene
Abstract Female neonates of the A, BALB/c, and C57BL/6 mouse strains were injected with androgen, estrogen, or oil and the effects upon their sex behavior studied. Genotype and treatment combined interactively on a substantial number of variables, indicating that the effects of perinatally administered sex hormones and genotype cannot be considered separately. Effects of the 2 hormones were often in different directions. The lordosis response of one genotype appeared relatively insensitive to neonatal treatment, particularly with androgen.