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Intense pulsed light for pigmented and vascular lesions and skin rejuvenation: Two decades of clinical trials
Author(s) -
Rachidi Saleh,
Goldberg David J.
Publication year - 2021
Publication title -
dermatological reviews
Language(s) - English
Resource type - Journals
ISSN - 2637-7489
DOI - 10.1002/der2.55
Subject(s) - intense pulsed light , dermatology , medicine , rejuvenation , actinic keratosis , hyperpigmentation , photoaging , clinical trial , randomized controlled trial , photodynamic therapy , pathology , surgery , chemistry , organic chemistry , basal cell
Background The wide wavelength spectrum of intense pulsed light (IPL) provides an opportunity for a versatile array of clinical applications in dermatology. Methods Key randomized clinical trials which took place in the past 20 years were summarized, focusing on skin rejuvenation, including pigmented and vascular lesions. We searched Pubmed using the key words intense, pulsed, light, and skin, then filtered results for randomized clinical trials. Results and Conclusions Studies uniformly showed improvement in pigmented and vascular lesions with IPL. Efficacy in treating rhytides was only observed in some studies. IPL was also effective as a light source in treating actinic keratosis with photodynamic therapy. Rare cases of post‐inflammatory hyperpigmentation were observed.