Open AccessMassive bleeding from a duodenal ulcer in a child with influenza infection: A case report of endoscopic findings
Author(s) -
Ishimoto Kenta,
Yoshimaru Koichiro,
Uchida Yasuyuki,
Kajihara Keisuke,
Obata Satoshi,
Matsuura Toshiharu,
Tajiri Tatsuro
Publication year - 2023
Publication title -
den open
Language(s) - English
Resource type - Journals
ISSN - 2692-4609
DOI - 10.1002/deo2.155
Subject(s) - medicine , melena , esophagogastroduodenoscopy , hematochezia , duodenum , duodenal bulb , gastroenterology , coagulopathy , perforation , capsule endoscopy , surgery , endoscopy , colonoscopy , materials science , colorectal cancer , cancer , punching , metallurgy
Gastrointestinal bleeding or perforation following influenza infection is rare. We encountered a pediatric case of hemorrhagic duodenal ulcer following influenza A infection. The patient was a 1‐year and 4‐month‐old boy who was diagnosed with influenza A infection and treated with laninamivir octanoate. After inhalation, he had diarrhea, poor appetite, and melena. The next day, he had hematochezia and developed hemorrhagic shock. Contrast‐enhanced computed tomography showed extravasation in the descending part of the duodenum. Esophagogastroduodenoscopy revealed spurting bleeding from a Dieulafoy's lesion on the oral side of the major papilla, and he underwent hemostasis by clipping. From the bulb to the descending part of the duodenum, the mucosa appeared atrophic with spotty redness on the circular folds and multiple and irregularly shaped erosions. Almost all mucosal lesions had healed by the eighth day, and he was monitored as an outpatient for more than one year without re‐bleeding. Intestinal ischemia, viral invasion, and drug reaction of laninamivir octanoate may be involved in duodenal mucosal injury. Acute duodenal ulcers may occur in children with influenza infection, especially young children.