Open AccessAcute necrotic disorder of the small intestine post‐coronavirus disease‐2019 vaccination
Author(s) -
Nishimura Tomoyuki,
Onogawa Seiji,
Yamamoto Takuya,
Okuda Yasuhiro,
Ikeda Morito,
Matsumoto Nozomu,
Kurihara Keisuke,
Shimizu Akinori,
Kitamura Shosuke,
Katamura Yoshio,
Hirano Naomichi,
Itamoto Shingo,
Nakahara Masahiro,
Yonehara Shuji,
Shimamoto Fumio,
Hanada Keiji
Publication year - 2023
Publication title -
den open
Language(s) - English
Resource type - Journals
ISSN - 2692-4609
DOI - 10.1002/deo2.137
Subject(s) - medicine , colonoscopy , vaccination , ileum , ileocecal valve , gastroenterology , coronavirus , covid-19 , abdominal pain , surgery , pathology , disease , colorectal cancer , cancer , infectious disease (medical specialty)
The Pfizer‐BioNTech coronavirus disease 2019 (COVID‐19) vaccine is extensively used worldwide, and its safety has been proven. Herein, we report a case of an acute necrotic disorder in the small intestine post‐COVID‐19 vaccination. The patient developed severe abdominal pain the day after the first vaccination. Contrast‐enhanced computed tomography showed extensive ileum wall thickening and ascites. Colonoscopy revealed a ring‐shaped ulcer and stricture in the terminal ileum. Ileocecal resection was performed, and the patient did not have further episodes of a necrotic disorder in the small intestine. Although it is unknown if this event is associated with vaccination, and this occurrence also does not outweigh the efficacy and safety of the Pfizer‐BioNTech COVID‐19 vaccine, gastroenterologists need to be aware of this rare case, given its noteworthy timing.