Premium
History of combinatorial chemistry
Author(s) -
Furka Árpád
Publication year - 1995
Publication title -
drug development research
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.582
H-Index - 60
eISSN - 1098-2299
pISSN - 0272-4391
DOI - 10.1002/ddr.430360102
Subject(s) - biochemical engineering , combinatorial chemistry , chemistry , computer science , chemical synthesis , engineering , biochemistry , in vitro
The paper describes and compares the utility of the three chemical methods used for the synthesis of combinatorial libraries: (1) the mixed reactant method, (2) the portioningmixing method, and (3) light‐directed synthesis. It also deals with historical aspects of these methods and with the most important screening methods associated with them. © 1995 Wiley‐Liss, Inc.