Premium
Interrelationship of general pharmacology studies with drug discovery and development, clinical medicine, and regulatory affairs
Author(s) -
Fossa Anthony A.,
Allan Buchholz R.
Publication year - 1994
Publication title -
drug development research
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.582
H-Index - 60
eISSN - 1098-2299
pISSN - 0272-4391
DOI - 10.1002/ddr.430320405
Subject(s) - clinical pharmacology , safety pharmacology , pharmacology , drug , systems pharmacology , drug discovery , medicine , drug development , bioinformatics , biology
General Pharmacology/Safety Pharmacology studies are being used increasingly to support registration of clinical drug candidates. The value of these studies and the possible impact on the drug discovery and development processes is being recognized as evidenced by the increasing number of companies implementing formal General Pharmacology/Safety Pharmacology groups. The interactions of other departments such as Discovery, Drug Metabolism, Toxicology, Clinical Medicine, and Regulatory Affairs with General Pharmacology are highly dependent on the positioning within the particular organization and the goals set for General Pharmacology studies. The nature of these interactions and how they can be used to the advantage of drug discovery and development programs are discussed.