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Effects of a low‐doses treatment with cuprum on neostigmine digestive action in female mice
Author(s) -
Santini R.,
Tessier M.,
Belon P.
Publication year - 1991
Publication title -
drug development research
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.582
H-Index - 60
eISSN - 1098-2299
pISSN - 0272-4391
DOI - 10.1002/ddr.430240304
Subject(s) - neostigmine , pharmacology , medicine , endocrinology
A low‐doses treatment with cuprum 4CH, 24 and 5 hr before neostigmine (50 μg/kg/IP) administration, has been done in the female mouse. This treatment significanlty reduces (Kruskal‐Wallis— P < 0.02) the facilitating action of neostigmine on intestinal transit. Cuprum 4CH treatment administered alone has no significant effect on transit.