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Phenomenology of schizophrenia and neuroleptic drugs
Author(s) -
Kendler Kenneth S.
Publication year - 1986
Publication title -
drug development research
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.582
H-Index - 60
eISSN - 1098-2299
pISSN - 0272-4391
DOI - 10.1002/ddr.430090103
Subject(s) - apathy , schizophrenia (object oriented programming) , psychiatry , thought disorder , psychology , psychosocial , psychosis , clinical psychology , psychotherapist , cognition
Abstract This paper reviews the penomenology of schizophrenia to acquaint non‐clinicans (pharmacology researchers) with the characteristic features of this disorder. Schizophrenia is noted to be a disorder with onset usually during early adult life in individuals who often have been at least mildly abnormal prior to the time of onset. The disorder is characterized by both positive symptoms, particularly delusions, hallucinations, thought disorder, and motoric symptoms, as well as negative symptoms, particularly affective flattening, avolition/apathy, and asociality. In most cases, schizophrenia leads to considerable psychosocial disability. Despite important advances in treatment, individuals who fully recover from schizophrenia remain relatively rare. New drugs are needed to treat this illness.