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Successful treatment of ballism with diazepam
Author(s) -
Becker Robert E.,
Lal Harbans,
Alexander Paul,
Karkalas John,
Kucharski Thomas
Publication year - 1982
Publication title -
drug development research
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.582
H-Index - 60
eISSN - 1098-2299
pISSN - 0272-4391
DOI - 10.1002/ddr.430020404
Subject(s) - diazepam , subthalamic nucleus , dopamine , medicine , pharmacology , drug , chemistry , deep brain stimulation , disease , parkinson's disease
Two patients with ballism were treated successfully with diazepam. It is suggested that diazepam acted as an indirect GABAmimetic drug to correct a functional GABA deficiency secondary to hyperactivity of the dopamine system in the subthalamic nucleus as a cause for ballism.
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