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Recent Advances on Bioactive Constituents in Ferula
Author(s) -
Zhou Yueting,
Xin Fang,
Zhang Guoqiang,
Qu Hexiang,
Yang Desong,
Han Xiaoqiang
Publication year - 2017
Publication title -
drug development research
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.582
H-Index - 60
eISSN - 1098-2299
pISSN - 0272-4391
DOI - 10.1002/ddr.21402
Subject(s) - coumarin , ferula , sesquiterpene , genus , antimicrobial , chemistry , traditional medicine , biology , organic chemistry , botany , medicine , splint (medicine) , physical therapy
Preclinical ResearchThe genus Ferula ( Umbelliferea ) is widely distributed across Central Asia and the Mediterranean. Some plants of the genus Ferula have been used as sources of pharmaceuticals for centuries. Ferula is a rich source of biologically active compounds, including coumarin derivatives, sesquiterpene‐substituted compounds, daucane esters, humulane, and germacrane compounds, aromatic lactones and disulfide compounds. Therefore, utilizing these bioactive constituents with antimicrobial and insecticidal effects not only can provide a new strategy for developing drug and green pesticide, but also protect endangered plant resources. In the present review, research advances on the bioactive constituents of the genus Ferula the plant sources. Drug Dev Res 78 : 321‐331, 2017. © 2017 Wiley Periodicals, Inc.