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Clinical significance of postprandial hyperglycemia
Author(s) -
Gerich John E.,
Woerle Hans J.
Publication year - 2006
Publication title -
drug development research
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.582
H-Index - 60
eISSN - 1098-2299
pISSN - 0272-4391
DOI - 10.1002/ddr.20128
Subject(s) - postprandial , glycemic , medicine , endocrinology , plasma glucose , limiting , diabetes mellitus , risk factor , mechanical engineering , engineering
This review will summarize evidence that postprandial hyperglycemia (1) is an independent risk factor for cardiovascular disease; (2) increases earlier and faster than fasting plasma glucose levels; and (3) contributes more to HbA 1c levels than fasting hyperglycemia when HbA 1c levels approach target values and, therefore, is the rate‐limiting factor for achieving optimal glycemic control. Finally, treatment recommendations will be presented. Drug Dev. Res. 67:587–590, 2006. © 2006 Wiley‐Liss, Inc.