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Alteration of wilms' tumor staging by cytologic detection of malignant cells in chylous ascites
Author(s) -
Baliga Mithra,
Holmquist Nelson,
Warrier Rajshekaran P.
Publication year - 1995
Publication title -
diagnostic cytopathology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.417
H-Index - 65
eISSN - 1097-0339
pISSN - 8755-1039
DOI - 10.1002/dc.2840120415
Subject(s) - medicine , wilms' tumor , chylous ascites , stage (stratigraphy) , lymph node , chyle , ascites , radiology , cytology , pathology , surgery , complication , paleontology , biology
Accurate staging as per National Wilms' Tumor Study (NWTS) criteria is essential for therapy of Wilms' tumor. We report a unique case of a 9‐mo‐old white male in whom the diagnosis based upon clinical, radiological, surgical, and initial histopathologic findings was Stage I Wilms' tumor without regard to a positive cytologic examination of a small amount (5 ml) of chylous ascitic fluid obtained intraoperatively. This problem was clarified later at the NWTS panel review when the deeper recuts of a renal hilar lymph node revealed a single cluster of Wilms' tumor cells in capsular sinus, resulting in upstaging of tumor to Stage III. the significance of these findings in relation to staging will be discussed. © 1995 Willey‐ Liss, Inc.