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Comparison of immunoreactivity of neu oncoprotein in fine‐needle aspirates and paraffin‐embedded materials
Author(s) -
Linder James,
Martin Alvin W.,
Davey Diane D.
Publication year - 1995
Publication title -
diagnostic cytopathology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.417
H-Index - 65
eISSN - 1097-0339
pISSN - 8755-1039
DOI - 10.1002/dc.2840120210
Subject(s) - medicine , pathology
Expression of the neu oncogene has been extensively examined in frozen and paraffin section breast cancers; however, very few studies examine neu oncoprotein expression in fine‐needle aspirates. to this effect, we compared the expression of neu oncoprotein in formalin‐fixed paraffin‐embedded breast cancers and the corresponding fine‐needle aspirates of these cancers. There was 100% correlation between the expression of neu oncoprotein in the paraffin‐embedded breast cancers and the fine‐needle aspirates, indicating the suitability of fine‐needle aspirates for the expression of neu oncoprotein in breast cancers. © 1995 Wiley‐ Liss, Inc.