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Melanocytic schwannoma: The cytologic aspect in fine‐needle aspiration cytology (FNAC): Report of a case located in the spinal cord
Author(s) -
SolaPérez J.,
PérezGuillermo M.,
BasBernal A.,
GiménezBascuñana A.,
MontesClavero C.
Publication year - 1994
Publication title -
diagnostic cytopathology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.417
H-Index - 65
eISSN - 1097-0339
pISSN - 8755-1039
DOI - 10.1002/dc.2840110319
Subject(s) - cytology , medicine , pathology , vimentin , spinal cord , fine needle aspiration cytology , schwannoma , intramedullary rod , magnetic resonance imaging , anatomy , radiology , immunohistochemistry , psychiatry
We describe a case of intramedullary melanocytic schwannoma (MS) studied by means of fine‐needle aspiration cytology (FNAC). The main cytologic features were (1) large three‐dimensional clusters overshadowed by heavy pigment deposits which tested positive for Fontana Masson (and bleached with potassium permanganate), HMB‐45, Vimentin, and S‐100 protein; (2) loose syncytial monolayered sheets with very little pigment deposit; and (3) isolated spindle cells with polarized nucleus and tapered, thin cytoplasmic ends. Both the cytologic features and the immunophenotypic profile were nonspecific and on their own were insufficient to allow the diagnosis of MS to be reached. Clinical data and the magnetic resonance image (MRI) in conjuction with the cytologic findings did suggest the diagnosis of intramedullary MS. Diagn Cytopathol 1994;11:291–296. © 1994 Wiley‐Liss, Inc.