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Fine‐needle aspiration of pancreatic extramedullary plasmacytoma: Possible confusion with islet cell tumor
Author(s) -
Dodd Leslie G.,
Evans Douglas B.,
Symmans Fraser,
Katz Ruth L.
Publication year - 1994
Publication title -
diagnostic cytopathology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.417
H-Index - 65
eISSN - 1097-0339
pISSN - 8755-1039
DOI - 10.1002/dc.2840100417
Subject(s) - pancreas , medicine , pathology , plasmacytoma , endocrine system , confusion , fine needle aspiration , immunohistochemistry , enteroendocrine cell , islet , neuroendocrine tumors , extramedullary plasmacytoma , multiple myeloma , biopsy , hormone , psychology , insulin , psychoanalysis
We report two cases of extramedullary plasmacytoma (EMP) of the pancreas, diagnosed by fine‐needle aspiration (FNA). Plasmacytoma of the pancreas is a rare neoplasm with only 12 cases recorded in the literature. Because of its scarcity and the cytomorphologic similarity between plasma cells and endocrine cells, EMP of the pancreas may be confused with neuroendocrine (islet cell) tumors of the pancreas. Immunohistochemical staining for light chain and/or neuroendocrine markers will prevent diagnostic error when interpreting plasmacytoid neoplasms of any site susceptible to endocrine tumors, including the pancreas. © 1994 Wiley‐Liss, Inc.