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Quality control study on negative gynecological cytology in Mexico
Author(s) -
LazcanoPonce Eduardo Cesar,
de Ruiz Patricia Alonso,
LopezCarrillo Lizbeth,
VazquezManriquez Maria Eugenia,
HernandezAvila Mauricio
Publication year - 1994
Publication title -
diagnostic cytopathology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.417
H-Index - 65
eISSN - 1097-0339
pISSN - 8755-1039
DOI - 10.1002/dc.2840100104
Subject(s) - medicine , papanicolaou stain , cytology , cervical cancer , christian ministry , cytopathology , gynecology , cervical cancer screening , cervix , obstetrics , cancer , pathology , philosophy , theology
An external evaluation of the quality of diagnosis of gynecological cytology specimens (Papanicolaou or “Pap” tests) in the Cytopathological Laboratory at the Mexico General Hospital was performed, with evaluation of 6,011 Pap tests randomly selected from 31,378 Pap studies previously reported as negative during 1988–1989. These tests were part of the early detection program for cervical cancer run by the Ministry of Health of Mexico City. A quality index for specimens was constructed based on the presence of endocervical cells, mucus, and squamous metaplastic cells. The index of false negatives for the diagnosis of cervical neoplasm in this sample which correspond to diagnostic error by the examiner was 0.18% (11). The constructed quality index revealed that 64.1% of specimens were low quality. The correlation between diagnostic error and low quality was .87. Results indicate that laboratories participating in early detection programs for cervical cancer in developing countries need to implement (1) external evaluation programs for Pap diagnosis; (2) permanent training programs in registration; and (3) monitoring procedures for collection, fixation, and transportation of cytologic materials. © 1994 Wiley‐Liss, Inc.