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Aspiration cytology of clear‐cell lesions of the parotid gland: Morphologic features and differential diagnosis
Author(s) -
Layfield Lester J.,
Glasgow Ben J.
Publication year - 1993
Publication title -
diagnostic cytopathology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.417
H-Index - 65
eISSN - 1097-0339
pISSN - 8755-1039
DOI - 10.1002/dc.2840090621
Subject(s) - medicine , mucoepidermoid carcinoma , acinic cell carcinoma , parotid gland , pathology , differential diagnosis , oncocytoma , cytopathology , myoepithelial cell , clear cell , carcinoma , cytology , fine needle aspiration , renal cell carcinoma , immunohistochemistry , biopsy
Clear‐cell lesions of the parotid gland are uncommon but when studied by fine‐needle aspiration may result in a clinically important but cytologically difficult differential diagnosis. Clear‐cell lesions involving the parotid include acinic cell neoplasm, clear cell oncocytoma, mucoepidermoid carcinoma, primary clear‐cell carcinoma, epithelial‐myoepithelial carcinoma, and metastatic renal cell carcinoma. Accurate diagnosis is achieved by assessment of nuclear features, other cell populations present, and clinical data including radiographic studies.