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Cytology of cardiac myxomas: Presence of ulex europaeus agglutinin‐I (UEA‐I) lectin by immunoperoxidase staining
Author(s) -
Iwa Nobuzo,
Yutani Chikao
Publication year - 1993
Publication title -
diagnostic cytopathology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.417
H-Index - 65
eISSN - 1097-0339
pISSN - 8755-1039
DOI - 10.1002/dc.2840090611
Subject(s) - ulex europaeus , lectin , immunoperoxidase , medicine , agglutinin , pathology , staining , cytology , immunology , antibody , monoclonal antibody
Abstract Cytological findings are presented of seven cases of cardiac myxomas. Avidin‐biotin‐peroxidase complex (ABC) method was employed to demonstrate Ulex europaeus agglutinin‐I (UEA‐I) lectin in imprint smears as well as in paraffin‐embedded tissue sections in cardiac myxomas. The cytology was characterized by tumor cells with polyhedral or stellate and mucinous background with lymphocytes, neutrophilles, and hemosiderin‐laden machrophages. In smears as well as tissue sections, UEA‐I lectin was detected throughout the cytoplasm of myxoma cells. This study established the applicability of the immunoperoxidase staining for cardiac myxoma as an aid in cytopathological diagnosis.