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Fine‐needle aspiration cytology of silicone granulomas in the augmented breast
Author(s) -
Dodd Leslie G.,
Sneige Nour,
Reece Gregory P.,
Fornage Bruno
Publication year - 1993
Publication title -
diagnostic cytopathology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.417
H-Index - 65
eISSN - 1097-0339
pISSN - 8755-1039
DOI - 10.1002/dc.2840090505
Subject(s) - giant cell , medicine , silicone , foreign body giant cell , cytopathology , histiocyte , biopsy , fine needle aspiration , cytology , pathology , fibroadenoma , breast cancer , cancer , chemistry , organic chemistry
We studied 12 aspirates from 10 patients who underwent diagnostic fine‐needle aspiration cytology (FNAC) of an augmented or reconstructed breast. Six patients were augmented with silicone gel‐filled implants and four patients had silicone liquid injections. FNAC indications included a painful or suspicious mass. Excisional biopsy was performed in six cases after FNAC. The findings of eight cases included modestly cellular smears composed of loosely cohesive histiocytes containing vacuoles of various sizes. Multinucleated foreign body giant cells, fragments of dense, amorphous fibrous tissue, and fibroblast nuclei stripped of cytoplasm were also present Two patients showed a mixture of inflammatory cells characteristic of intramammary lymph nodes or lymphoid aggregates. We conclude that silicone granulomas of the breast show a characteristic set of findings on FNAC which enable a cytopathologist to render a specific diagnosis given an appropriate history of breast augmentation. Diagn Cytopathol 1993;9:498‐502. © 1993 Wiley‐Liss, Inc.