Premium
Histiocytic necrotizing lymphadenitis (kikuchi's disease): Cytologic diagnosis by fine‐needle biopsy
Author(s) -
Greenberg Merle L.,
Cartwright Lyn,
McDonald David A.
Publication year - 1993
Publication title -
diagnostic cytopathology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.417
H-Index - 65
eISSN - 1097-0339
pISSN - 8755-1039
DOI - 10.1002/dc.2840090414
Subject(s) - medicine , pathology , histiocyte , cervical lymphadenopathy , biopsy , hepatosplenomegaly , differential diagnosis , cytology , histology , lymphoma , disease
Abstract A cytologic diagnosis of histiocytic nerotizing lymphadenitis (Kikuchi's lymphadenitis) was made in a 14‐yr‐old female with cervical lymphadenopathy, Fever, neutropenia, and hepatosplenomegaly. A predominance of reticulum cells, foamy macrophages, and karyorrhectic debirs are cluse to the diagnosis in the fine‐needle biopsy smears. Subsequent histology confirmed the diagnosis of Kikuchi's lymphadenitis. The differential diagnoses are discussed including malignant lymphoma, which was excluded by morphology as well as flow cytometry and polymerase chain reaction (PCR) studies.