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Testicular cytology in azoospermia
Author(s) -
Verma Anand Kumar,
Basu Debdatta,
Jayaram Gita
Publication year - 1993
Publication title -
diagnostic cytopathology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.417
H-Index - 65
eISSN - 1097-0339
pISSN - 8755-1039
DOI - 10.1002/dc.2840090108
Subject(s) - azoospermia , medicine , sertoli cell , cytology , spermatogenesis , hyperplasia , leydig cell , leydig cell tumor , andrology , cytopathology , urology , testicular sperm extraction , pathology , gynecology , infertility , luteinizing hormone , biology , hormone , pregnancy , genetics
Abstract Two hundred‐seventy‐five azoospermic mates were subjected to fine‐needle aspiration (FNA) cytologic study of testis with the aim of determining the cause of azoospermia; 534 aspirates from these patients were classified as follows: normal spermatogenesis (162), hypospermatogenesis (mild, moderate, or severe, 226), absence of spermatogenesis (130), maturation arrest (36), Sertoli‐cell‐only syndrome (14), and Leydig‐cell hyperplasia (3). The morphology of cells was excellent in the cytologic preparations and various spermatogenic cells and Sertoli cells were easily recognized. Leydig cells were uncommonly seen, except in cases of Leydig‐cell hyperplasia. Degenerative changes, possibly due to obstruction, were seen in 104 cases. The procedure was well tolerated by the patients. We conclude that FNA cytology is a useful investigative modality in the evaluation of azoospermic males.