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Accuracy of bronchial aspiration cytology in typing operable (stage I‐II) pulmonary carcinomas
Author(s) -
Barbazza Renzo,
Toniolo Lamberto,
Pinarello Antonella,
Scapinello Antonio,
Falconieri Giovanni,
Bonito Luigi Di
Publication year - 1992
Publication title -
diagnostic cytopathology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.417
H-Index - 65
eISSN - 1097-0339
pISSN - 8755-1039
DOI - 10.1002/dc.2840080103
Subject(s) - medicine , adenocarcinoma , stage (stratigraphy) , cytology , carcinoma , lung cancer , pathology , typing , histology , large cell , lung , cancer , small cell carcinoma , respiratory disease , oncology , biology , paleontology , genetics
The accuracy of bronchial aspiration cytology in typing resectable (stage I‐II) lung cancer has been investigated in 100 cases, comparing preoperative cytologic features with pulmonary tumor histology seen at surgery. The accuracy has been 100% for small‐cell carcinoma (two cases), 98.8% for squamous‐cell carcinoma (86 cases), and 91.6% for adenocarcinoma (12 cases). The overall accuracy rate has been 98%. No case of undifferentiated large‐cell carcinoma has been identified. It is suggested that the high accuracy in cytologic typing of operable lung cancer is basically related to adequate preservation of differentiation features, thus allowing for correct identification of most non‐small‐cell carcinoma. Moreover, the absence in this study of any large‐cell carcinoma, compared with its frequency in advanced stage series, would indicate that such a histotype reflects excessive dedifferentiation of an original squamous or glandular form.