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Leydig cell tumor of the testis: A case diagnosed by fine‐needle sampling without aspiration with histologic, immunohistologic, and electron microscopic analysis
Author(s) -
Vielh Philippe,
Borghesi Rita,
Validire Pierre,
Zajdela Antoine
Publication year - 1991
Publication title -
diagnostic cytopathology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.417
H-Index - 65
eISSN - 1097-0339
pISSN - 8755-1039
DOI - 10.1002/dc.2840070610
Subject(s) - pathology , medicine , endoplasmic reticulum , cytology , vimentin , fine needle aspiration , giemsa stain , sampling (signal processing) , cytopathology , papanicolaou stain , tumor cells , fine needle aspiration cytology , immunohistochemistry , anatomy , biopsy , biology , cancer , microbiology and biotechnology , filter (signal processing) , cancer research , computer science , computer vision , cervical cancer
Fine‐needle sampling without aspiration was performed in a patient with a testicular mass. The cytologic diagnosis was consistent with Leydig cell tumor. Cytologic features included abundant grey‐blue cytoplasms with spherical or oval nuclei in May‐Grünwald‐Giemsa‐stained smears. Intranuclear inclusions were observed but no Reinke's crystals were detected. Histologic findings confirmed the diagnosis and tumor cells were positive for vimentin. Electron microscopic analysis of the tumor showed abundant smooth endoplasmic reticulum and mitochondria with tubulovesicular cristae but no Reinke's crystals.