Rhabdomyosarcomatous differentiation in a neuroblastoma: A potential pitfall in the cytologic diagnosis of small round‐cell tumors of childhood | Zendy

Layfield Lester J. | Zendy; Glasgow Ben J. | Zendy

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Rhabdomyosarcomatous differentiation in a neuroblastoma: A potential pitfall in the cytologic diagnosis of small round‐cell tumors of childhood

Author(s) -

Layfield Lester J.,

Glasgow Ben J.

Publication year - 1991

Publication title -

diagnostic cytopathology

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 0.417

H-Index - 65

eISSN - 1097-0339

pISSN - 8755-1039

DOI - 10.1002/dc.2840070218

Subject(s) - medicine , rhabdomyosarcoma , neuroblastoma , desmin , pathology , fine needle aspiration , cytology , neoplasm , stromal cell , immunohistochemistry , sarcoma , biopsy , vimentin , cell culture , biology , genetics

Rhabdomyoblasts demonstrating immunoreactivity for musclespecific actin, desmin, and myoglobin were identified in smears obtained by aspiration from a large retroperitoneal mass in a 14‐mo‐old girl. Following a tentative diagnosis of a rhabdomyogenous neoplasm, retroperitoneal exploration and adrenalectomy demonstrated a stromal poor neuroblastoma with extensive rhabdomyogenous differentiation. The presence of a subpopulation of rhabdomyoblasts was not diagnostic of rhabdomyosarcoma when obtained by fine‐needle aspiration from a retroperitoneal tumor composed predominantly of primitive small round cells.

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