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Diagnosis of pulmonary blastoma by fine‐needle aspiration biopsy: Cytologic and immunocytochemical findings
Author(s) -
Cosgrove Michele M.,
Chandrasoma Parakrama T.,
Martin Sue Ellen
Publication year - 1991
Publication title -
diagnostic cytopathology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.417
H-Index - 65
eISSN - 1097-0339
pISSN - 8755-1039
DOI - 10.1002/dc.2840070122
Subject(s) - medicine , pulmonary blastoma , papanicolaou stain , pathology , cytology , fine needle aspiration , biopsy , cytopathology , radiology , fine needle aspiration cytology , lung , cancer , cervical cancer
A preoperative diagnosis of pulmonary blastoma was established by fine‐needle aspiration (FNA) cytology in a patient who presented with a pulmonary mass discovered incidentally on chest x‐ray. At the time of computed tomography‐guided FNA, an on‐site preliminary diagnosis of poorly differentiated carcinoma was made after examination of a rapid hematoxylineosin (H a E)‐stained smear. Malignant epithelial and stromal elements could be demonstrated on smears subsequently stained with the H&E, Papanicolaou, and Diff‐Quik methods. The cell block preparation showed a distinctly biphasic malignant tumor with classic morphologic features of pulmonary blastoma. We present the clinical, cytologic, immunocytochemical, and histologic findings of this case and re‐emphasize the valuable contribution of adequate cell block preparations to accurate diagnosis of fine‐needle aspiration material.