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Tissue imprints in surgical pathology: A rapid intraoperative diagnostic aid
Author(s) -
Scopa Chrisoula D.,
Melachrinou Maria,
Apessou Demetra,
Bonikos Dionysis
Publication year - 1990
Publication title -
diagnostic cytopathology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.417
H-Index - 65
eISSN - 1097-0339
pISSN - 8755-1039
DOI - 10.1002/dc.2840060103
Subject(s) - medicine , frozen section procedure , malignancy , cytology , radiology , diagnostic accuracy , surgical pathology , stain , cytopathology , pathology , staining
We studied the intraoperative diagnostic value of imprint cytology in 230 samples obtained from surgical specimens submitted for frozen section diagnosis. A rapid hematoxylineosin stain was used. Intraoperative imprint cytology achieved an accuracy rate of 94.3%; for benign lesions the accuracy was 97.5%, and for malignant lesions it was 91%. Overall, the false‐negative and suspicious‐for‐malignancy rates were 1.3% and 4.3%, respectively. No false‐positive results were found. The diagnostic yield when intraoperative imprint cytology and frozen section were used together was 99%. It is apparent that imprint cytology is a quick and simple method with wide applicability in the histopathologic diagnosis of lesions from all organs. The value of the method is enhanced when it is used with frozen section diagnosis.