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False‐positive diagnosis in fine‐needle aspiration of an atypical Warthin's tumor: Histochemical differential stains for cytodiagnosis
Author(s) -
Laucirica Rodolfo,
Farnum James B.,
Leopold Sophie K.,
Kalin George B.,
Youngberg George A.
Publication year - 1989
Publication title -
diagnostic cytopathology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.417
H-Index - 65
eISSN - 1097-0339
pISSN - 8755-1039
DOI - 10.1002/dc.2840050415
Subject(s) - pathology , medicine , immunoperoxidase , cytology , differential diagnosis , fine needle aspiration , cytopathology , biopsy , antibody , immunology , monoclonal antibody
Cytologic smears of a Warthin's tumor (WT) typically consist of sheets of oncocytic (oxyphilic) cells and scattered lymphocytes. Reparative foci within this neoplasm can occur, which may give rise to exfoliated, malignant‐appearing, squamouslike cells. A false‐positive diagnosis of squamous carcinoma can occur when these atypical cells dominate the cytologic aspirate. Histochemical and immunoperoxidase stains may aid in diagnosing an atypical WT when the usual cytologic features are absent.