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Papillary carcinoma of prostatic ductal origin: A cytologic case report with immunohistochemical and quantitative dna correlation
Author(s) -
Howell Lydia P.,
Teplitz Raymond L.
Publication year - 1989
Publication title -
diagnostic cytopathology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.417
H-Index - 65
eISSN - 1097-0339
pISSN - 8755-1039
DOI - 10.1002/dc.2840050219
Subject(s) - pathology , medicine , cytology , malignancy , prostate , immunohistochemistry , carcinoma , biopsy , cancer
This report describes the aspiration biopsy cytology (ABC) of a case of papillary carcinoma of ductal origin, an uncommon malignant tumor of the prostate. Only one case has been previously reported in the cytology literature. Atypical papillary fragments are the distinctive cytologic findings. Similar to well‐differentiated acinar carcinoma of the prostate, the cytologic features of malignancy in this lesion may be subtle, and diagnosis is based on the presence of the cytologic pattern. Positive immunohistochemical staining with prostate‐specific acid phosphatase confirms the prostatic origin. Application is made of quantitative DNA analysis for prognostic determination.