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Mucinous metaplasia to neoplastic lesions in endometrial samples with cytohistologic correlation
Author(s) -
GaleraDavidson H.,
Fernandez A.,
Navarro J.,
Parrilla A.,
Salguero M.,
Rivera F.
Publication year - 1989
Publication title -
diagnostic cytopathology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.417
H-Index - 65
eISSN - 1097-0339
pISSN - 8755-1039
DOI - 10.1002/dc.2840050208
Subject(s) - adenocarcinoma , medicine , pathology , metaplasia , cytology , endometrium , cytopathology , cancer
Seven cases of endometrial mucinous metaplasia and five of well‐differentiated mucinous adenocarcinoma of the endometrium were studied. Cytologic specimens were obtained by Isaacs endometrial sampler, avoiding endocervical contamination. The histologic diagnosis between the intermediate type of mucinous metaplasia and the well‐differentiated mucinous adenocarcinoma posed no problems. DNA analyses of the histologic samples showed a euploid pattern in benign and intermediate types of metaplasia, while well‐differentiated mucinous adenocarcinoma showed a hyperdiploid pattern. The cytologic diagnosis of benign mucinous metaplasia should be suggested in the presence of abundant mucinous cells in endometrial samples in the absence of nuclear abnormalities.