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The value of endometrial cytology by scraping in 1, 798 cases: Screening in asymptomatic women and diagnosis in symptomatic ones
Author(s) -
Porrazzi Luigi Coscia,
Quarto Ferdinando,
Maiello Francesco M.,
De Falco Maria L.,
Antonucci Tiziana
Publication year - 1987
Publication title -
diagnostic cytopathology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.417
H-Index - 65
eISSN - 1097-0339
pISSN - 8755-1039
DOI - 10.1002/dc.2840030205
Subject(s) - medicine , asymptomatic , curettage , endometrial hyperplasia , endometrial cancer , hyperplasia , cytology , gynecology , population , atypical hyperplasia , cancer , pathology , environmental health
A study of 1,798 endometrial cytological samples, obtained with an “endocyte” (a disposable scraping device) and controlled in histology is presented. The method was tested for its usefulness in screening of precancerous lesions and preclinical cancer in 1,248 asymptomatic women and in the diagnosis of endometrial pathology in 550 symptomatic ones. The classification of hyperplasia into benign simplex and complex hyper‐plasia and atypical hyperplasia was followed; atypical hyperplasia, considered real intraepithelial neoplasia, was included in the positive cases. Histological verification was made chiefly on cell block in asymptomatic cytologically negative cases and either on curettage or hysterectomies in the others. The main endometrial cytological patterns are described. On the basis of findings, considering also endocyte's low cost, effectiveness, and ease of use, we think the method could be usefully employed in screening of endometrial cancer for an asymptomatic population. In symptomatic women, the use of histologic procedures is still preferable, and cytology cannot be considered a “first option” method. Diagn Cytopathol 1987;3:112–120.