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Psammoma bodies and optically clear nuclei in bronchiolo‐alveolar cell carcinoma. Diagnosis by fine needle aspiration biopsy with histologic and ultrastructural confirmation
Author(s) -
Silverman Jan F.,
Finley James L.,
Park H. Kim,
Norris H. Thomas,
Strausbauch Paul H.
Publication year - 1985
Publication title -
diagnostic cytopathology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.417
H-Index - 65
eISSN - 1097-0339
pISSN - 8755-1039
DOI - 10.1002/dc.2840010308
Subject(s) - psammoma body , pathology , medicine , cytopathology , cytology , lung , fine needle aspiration , carcinoma , biopsy , immunohistochemistry
The fine needle aspiration cytology of two cases of bronchiolo‐alveolar cell carcinoma of the lung having unusual features is reported. One case demonstrated numerous psammoma bodies in the cytologic smears, whereas the other case showed an abundance of cells with optically clear nuclei. Both peripherally located tumors were resected and confirmed as primary bronchiolo‐alveolar cell carcinoma by histologic and ultra‐structural examination. We believe this to be the first report describing these unusual features of bronchiolo‐alveolar cell carcinoma diagnosed by fine needle aspiration cytology. Presented is a discussion of psammoma bodies and optically clear nuclei seen in primary and metastatic tumors of the lung. This will aid in the diagnosis of these cases. Diagn Cytopathol 1985;1:205–15.