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Crystal‐storing histiocytes in ascites leading to a diagnosis of plasma cell myeloma
Author(s) -
Hamadeh Fatima,
Smith Mitchell R.,
Hsi Eric D.
Publication year - 2021
Publication title -
diagnostic cytopathology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.417
H-Index - 65
eISSN - 1097-0339
pISSN - 8755-1039
DOI - 10.1002/dc.24755
Subject(s) - medicine , multiple myeloma , ascites , pathology , histiocyte , plasma cell , plasma cell myeloma , eosinophilic , malignant histiocytosis , histiocytosis , plasmacytoma , myeloma protein , lymphoproliferative disorders , spleen , bone marrow , lymphoma , disease
Histiocytes containing multiple needle‐shaped eosinophilic crystals visualized in a peritoneal fluid sample during evaluation of a patient for liver transplantation led to the diagnosis of unsuspected IgA kappa myeloma. Crystal‐storing histiocytosis is a rare phenomenon typically associated with multiple myeloma and B‐cell lymphoproliferative disorders. It can involve almost any anatomic site and can occasionally be seen in body fluid samples.