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Accuracy of fine‐needle aspiration cytology in the diagnosis of salivary gland masses according to the Milan reporting system and to an in‐house system
Author(s) -
Rammeh Soumaya,
Romdhane Emna,
Ksentini Meriem,
Belhajkacem Linda,
Znaidi Nadia,
Riahi Ines,
Lahiani Rim,
Ben Salah Mamia
Publication year - 2021
Publication title -
diagnostic cytopathology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.417
H-Index - 65
eISSN - 1097-0339
pISSN - 8755-1039
DOI - 10.1002/dc.24682
Subject(s) - medicine , atypia , cytopathology , malignancy , gold standard (test) , fine needle aspiration cytology , salivary gland , cytology , diagnostic accuracy , medical diagnosis , histopathology , predictive value , radiology , pathology
Background This study aims to assess in our institutional experience the accuracy of fine needle aspiration cytology (FNAC) in the diagnosis of salivary gland masses (SGM) according to the Milan System for Reporting Salivary Gland Cytopathology (MSRSGC) and to an in‐house system. Methods The study included 189 FNACs conducted between January 2011 and December 2019. The FNACs, classified according to the in‐house system, were reclassified according the MSRSGC. Taking histopathology as gold standard, the measures of diagnostic accuracy of FNAC were determined for suspicion for malignancy (SFM) and malignant categories. Results According to the in house system, FNAC diagnoses were classified as: 23 (12.2%) non‐diagnostic (ND), 23 (12.2%) non‐neoplastic (NN), 119 (62.9%) benign neoplasm (BN), 10 (5.2%) indefinite neoplasm (IN), 2 (1.1%) SFM, and 12 (6.4%) malignant (M). Based on the MSRSGC, there were 3 (1.5%) cases of atypia of undetermined significance (AUS) and 7 (3.7%) neoplasms of uncertain malignant potential (SUMP). The number of ND, NN, BN, SFM, and M cases were identical in the two systems. For both systems, the sensitivity, the specificity, the positive predictive value, the negative predictive value, and the accuracy for malignancy diagnosis were 77.8%, 100%, 100%, 97.6%, and 97.8%, respectively. Conclusion According to the MSRGC and to our in‐house reporting system, FNAC is an accurate technique for the diagnosis of malignant salivary tumors with excellent specificity and good sensitivity. However, MSRGC has the advantage of standardization of salivary gland cytology reporting.