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Giant cell‐rich extrapleural solitary fibrous tumor: Cytological findings and differential diagnosis of a rare neoplasm
Author(s) -
Ronchi Andrea,
Cozzolino Immacolata,
Montella Marco,
Donadio Anna,
Motta Gaetano,
Franco Renato,
Palombini Lucio
Publication year - 2021
Publication title -
diagnostic cytopathology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.417
H-Index - 65
eISSN - 1097-0339
pISSN - 8755-1039
DOI - 10.1002/dc.24610
Subject(s) - medicine , differential diagnosis , fine needle aspiration cytology , neoplasm , pathology , solitary fibrous tumor , head and neck , cytology , mesenchymal stem cell , cytopathology , surgery , cd34 , biology , stem cell , genetics
Abstract Extrapleural solitary fibrous tumor (ESFT) is a rare neoplasm with a variable biological behavior that may occur almost everywhere in the body, as it has been reported in head and neck, back, retroperitoneum, inguinal region and more. The diagnosis of ESFT may be challenging, especially in case of its morphological rare variants such as giant cell‐rich ESFT. Fine‐needle aspiration cytology (FNAC) is a rapid, poorly invasive, safe diagnostic technique, which is recently proving useful for the preoperative diagnosis of mesenchymal neoplasms. Herein we report a case of a FNAC diagnosis of giant cell‐rich ESFT, focusing on its morphological and immunocytochemical characteristics, and showing how cytology may be an effective tool in the preoperative diagnosis of mesenchymal neoplasms, allowing the correct surgical management of the patient.