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Amelanotic melanoma recurrence diagnosed by fine‐needle aspiration cytology: A case report
Author(s) -
Khairwa Anju
Publication year - 2020
Publication title -
diagnostic cytopathology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.417
H-Index - 65
eISSN - 1097-0339
pISSN - 8755-1039
DOI - 10.1002/dc.24529
Subject(s) - amelanotic melanoma , medicine , melanoma , pathology , immunohistochemistry , histology , differential diagnosis , cytology , fine needle aspiration cytology , cancer research
Amelanotic melanoma is a variant of malignant melanoma. Amelanotic melanoma has similar morphology of a wide variety of epithelial and non‐epithelial malignant tumours, variable cytomorphology of melanoma has been described on exfoliative and fine‐needle aspiration cytology (FNAC). Aim of index study to describe FNAC of a rare case of recurrent amelanotic melanoma of right lateral knee swelling. Case: A 37‐year‐old male presented right lateral knee multi‐nodular swelling last for 1 month with history of similar swelling 6 months back and operated. Histologically it was reported amelanotic malignant melanoma. FNAC revealed mordantly pleomorphic malignant cells predominantly plasmacytoid, plump shaped, prominent single to multiple nucleoli along with bi‐nucleated and multi‐nucleated tumour giant cells were also noted. Histology and immunohistochemistry (IHC) slides were reviewed and confirm the diagnosis. Concluded amelanotic melanoma has highly varied cytomorphology with multiple differential diagnosis and IHC markers are of great value for final diagnosis of it.