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Reproducibility of “the Papanicolaou Society of Cytopathology system for reporting respiratory cytology” – A retrospective analysis of 101 cases of CT ‐guided FNAC
Author(s) -
Boler Anup Kumar,
Banu Nasreen,
Bose Koushik,
Roy Shreosee,
Bandyopadhyay Arghya
Publication year - 2020
Publication title -
diagnostic cytopathology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.417
H-Index - 65
eISSN - 1097-0339
pISSN - 8755-1039
DOI - 10.1002/dc.24452
Subject(s) - medicine , cytopathology , papanicolaou stain , kappa , cohen's kappa , cytology , reproducibility , malignancy , radiology , papanicolaou test , pathology , cancer , statistics , linguistics , philosophy , mathematics , cervical cancer
Guided fine‐needle aspiration cytology is a popular investigative procedure in diagnosing pulmonary lesions. The Papanicolaou Society of Cytopathology (PSC) has already outlined a categorical system for reporting respiratory cytology. Though each category has a known malignancy risk, their inter observer reproducibility have not been well documented. This study was directed towards establishing the reproducibility of this categorical system in diagnosing pulmonary lesions. Method One hundred and one consecutive cytology specimens obtained by CT‐guided FNA from lung lesions were independently reviewed by 3 experienced cytopathologists, who allotted each case to 1 of 6 PSC categories. Statistical analysis for percent overall agreement was done using Fleiss' Kappa. Result Percent overall agreement was 71.29% and free marginal kappa was 0.66. On combining categories “suspicious” and “malignant” percent overall agreement was 79.54% and free marginal kappa was 0.74. Conclusion There was substantial agreement among the observers as regards reproducibility of categories which can improve if we combine certain categories, especially “suspicious” and “malignant.”