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Cytological diagnosis of juvenile xanthogranuloma: A rare histiocytic disorder
Author(s) -
Chauhan Shivangi,
Diwaker Preeti,
Singh Aakanksha,
Gogoi Priyanka,
Arora Vinod K.
Publication year - 2020
Publication title -
diagnostic cytopathology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.417
H-Index - 65
eISSN - 1097-0339
pISSN - 8755-1039
DOI - 10.1002/dc.24310
Subject(s) - juvenile xanthogranuloma , medicine , histopathology , histiocyte , pathology , biopsy , scalp , dermatology
Abstract Juvenile xanthogranuloma (JXG) is a rare type of non‐Langerhan cell histiocytic disorder, which is mostly confined to skin of head and neck. It is a self‐limiting benign condition, which does not require surgery. We present a case of 8‐month‐old girl child with multiple yellowish brown colored papules over scalp, face, and neck. A clinical diagnosis of cutaneous mastocytosis was made. Fine‐needle aspiration cytology (FNAC) smears showed foamy macrophages along with mixed inflammatory infiltrate and few touton giant cells. A diagnosis of JXG was rendered which was confirmed on histopathology and immunohistochemistry.Juvenile xanthogranuloma can be diagnosed on FNAC based on its characteristic cytologic features; however, it requires a high index of suspicion by cytopathologist. Cytological diagnosis of JXG can save the patient from unnecessary surgical biopsy or excision.