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Poorly differentiated vaginal adenocarcinoma with aggressive behavior—Pap smear findings
Author(s) -
Eleutério José,
de Freitas Francisca Margalene Medeiros,
Oliveira Denise Nunes,
Moreira David Freitas,
Pessoa Mirley Sângela
Publication year - 2017
Publication title -
diagnostic cytopathology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.417
H-Index - 65
eISSN - 1097-0339
pISSN - 8755-1039
DOI - 10.1002/dc.23774
Subject(s) - medicine , vagina , vaginal bleeding , adenocarcinoma , cervix , cytology , papanicolaou stain , biopsy , gynecology , pathology , surgery , cancer , cervical cancer , pregnancy , biology , genetics
Vaginal carcinoma is a rare condition. In this report, we describe a case of a poorly differentiated aggressive adenocarcinoma in a woman with a three month history of vaginal bleeding and a negative Pap smear done six months prior to her consultation. Specular examination showed a normal cervix, but there was a bleeding ulcer (2 cm in diameter) in the upper third of the vagina. Cytology revealed poorly differentiated atypical cells, and the biopsy established a diagnosis of vaginal adenocarcinoma with little differentiation. Within two months, the patient died without diagnosis of a primary tumor site other than the vagina.