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Metastatic tonsillar squamous cell carcinoma masquerading as a pancreatic cystic tumor and diagnosed by EUS‐guided FNA
Author(s) -
Glass Ryan,
Andrawes Sherif A.,
HameleBena Diane,
Tong GuoXia
Publication year - 2017
Publication title -
diagnostic cytopathology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.417
H-Index - 65
eISSN - 1097-0339
pISSN - 8755-1039
DOI - 10.1002/dc.23769
Subject(s) - medicine , pancreas , pathology , metastatic carcinoma , fine needle aspiration , differential diagnosis , head and neck squamous cell carcinoma , metastasis , carcinoma , biopsy , radiology , radiation therapy , head and neck cancer , cancer
Metastatic carcinoma to the pancreas is uncommon and head and neck squamous carcinoma metastatic to the pancreas is extremely rare. Metastatic squamous cell carcinoma to the pancreas presents a unique diagnostic challenge: in addition to mimicking the rare primary squamous cell carcinoma of the pancreas based on cytologic, histologic, and immunohistochemical features, it may be mistaken for a cystic neoplasm of the pancreas because of its high predilection for cystic degeneration in metastatic sites. Herein, we report a case of tonsillar squamous cell carcinoma with a cystic pancreatic metastasis diagnosed by ultrasound‐guided fine needle aspiration biopsy (EUS‐FNA). This represents a third reported case of metastatic squamous cell carcinoma to the pancreas from the head and neck region. Metastatic squamous cell carcinoma should be considered in the differential diagnosis of EUS‐FNA during evaluation of pancreatic cystic lesion.