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Lower respiratory tract viral infections: Diagnostic role of exfoliative cytology
Author(s) -
MartínezGirón Rafael,
Pantanowitz Liron
Publication year - 2017
Publication title -
diagnostic cytopathology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.417
H-Index - 65
eISSN - 1097-0339
pISSN - 8755-1039
DOI - 10.1002/dc.23697
Subject(s) - exfoliative cytology , medicine , respiratory tract , pathology , immunoassay , isolation (microbiology) , cytology , respiratory tract infections , viral infection , immunology , antibody , respiratory system , virus , biology , microbiology and biotechnology
Viral lower respiratory tract infections (VLRTI) remain one of the most common causes of morbidity and mortality worldwide. For many years, the diagnosis of VLRTI was based on laboratory techniques such as viral isolation in cell culture, antigen detection by direct fluorescent antibody staining, and rapid enzyme immunoassay. Radiological imaging and morphology also play an important role in diagnosing these infections. Exfoliative cytology provides a simple, rapid, inexpensive, and valuable means to diagnose and manage VLRTI. Here we review viral‐associated cytomorphological changes seen in exfoliated cells of the lower respiratory tract. Diagn. Cytopathol. 2017;45:614–620. © 2017 Wiley Periodicals, Inc.