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Primary anorectal mucosal melanoma detected by anorectal cytology
Author(s) -
Lau Ryan Paul,
Chiaffarano Jeanine,
Alexander Melissa,
Octavius Jolene,
Azar Omar,
Shi Yan,
YeeChang Melissa
Publication year - 2017
Publication title -
diagnostic cytopathology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.417
H-Index - 65
eISSN - 1097-0339
pISSN - 8755-1039
DOI - 10.1002/dc.23675
Subject(s) - medicine , cytology , pathology , dysplasia , intraepithelial neoplasia , anal canal , melanoma , anus , basal cell , rectum , cancer , gastroenterology , cancer research , anatomy , prostate
The detection of primary anorectal melanoma on anal cytology is a rare and challenging diagnosis. We report a case where anorectal cytology showed isolated malignant cells with oval nuclei, prominent nucleoli, and elongated wispy cytoplasmic projections. There was no evidence of squamous dysplasia or melanin pigment identified. To the best of our knowledge, this is the first reported case of a primary anorectal melanoma detected in anorectal cytology. Detection of malignancies other than squamous cell carcinoma can be seen on anorectal cytology and should be considered when there is no evidence of anal intraepithelial neoplasia. Diagn. Cytopathol. 2017;45:452–455. © 2017 Wiley Periodicals, Inc.