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Urine cytology findings of primary paraganglioma of the urinary bladder: Case report
Author(s) -
Lee Junghye,
Park Sanghui,
Cho MinSun,
Sung Sun Hee,
Kim Kwang Hyun
Publication year - 2017
Publication title -
diagnostic cytopathology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.417
H-Index - 65
eISSN - 1097-0339
pISSN - 8755-1039
DOI - 10.1002/dc.23667
Subject(s) - cystoscopy , chromogranin a , urine cytology , pathology , medicine , cystectomy , cytoplasm , urinary bladder , paraganglioma , synaptophysin , cytology , urine , epithelioid cell , urinary system , urothelial cell , trigone of urinary bladder , urology , immunohistochemistry , anatomy , biology , urothelium , bladder cancer , biochemistry , cancer , alternative medicine
Paraganglioma (PG) of the urinary bladder was detected in a 64‐year‐old male who was admitted to the hospital with gross hematuria. In voided urine, atypical cells were scattered as nests and single cells on low‐power view. On higher‐power view, tumor nests were composed of epithelioid cells with fine chromatin and moderate cytoplasm admixed with occasional spindle sustentacular cells. Single cells were discohesive and large with moderate cytoplasm and inconspicuous nucleoli. Subsequent cystoscopy revealed a solid oval mass. Histologically, tumor from the resected bladder showed infiltrating nested tumor cells with abundant cytoplasm. Immunohistochemically, the tumor cells were positive for synaptophysin, chromogranin, and CD56. The patient underwent partial cystectomy and was discharged without complications. Diagn. Cytopathol. 2017;45:350–353. © 2016 Wiley Periodicals, Inc.