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Pleural fluid extramedullary hematopoiesis case report with review of the literature
Author(s) -
Koch Meghan,
Kurian Elizabeth M.
Publication year - 2016
Publication title -
diagnostic cytopathology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.417
H-Index - 65
eISSN - 1097-0339
pISSN - 8755-1039
DOI - 10.1002/dc.23390
Subject(s) - extramedullary hematopoiesis , myelofibrosis , medicine , pathology , haematopoiesis , serous fluid , bone marrow , pleural fluid , pleural effusion , radiology , stem cell , genetics , biology
Extramedullary hematopoiesis (EMH) is the trilineage formation of normal blood cells outside of the bone marrow. While predominantly seen in the spleen and liver, EMH rarely occurs in serous effusions. Accurate diagnosis requires recognition of megakaryocytes and other precursor hematopoietic elements. We present a case of pleural fluid EMH in a patient with primary myelofibrosis and developing leukemia, with a review of the literature, prognostic implications and diagnostic challenges. Diagn. Cytopathol. 2016;44:41–44. © 2015 Wiley Periodicals, Inc.